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VAMP 1,2 anticorps

Cet anticorps anti- est un anticorps Souris Monoclonal détectant dans IHC et WB. Adapté pour Humain.
Rockland
N° du produit ABIN6656054
N° du produit (Fournisseur): 200-301-e34

Aperçu rapide pour VAMP 1,2 anticorps (ABIN6656054)

Antigène

VAMP 1,2

Reactivité

Humain

Hôte

  • 1
Souris

Clonalité

  • 1
Monoclonal

Conjugué

  • 1
Inconjugué

Application

  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Western Blotting (WB)

Clone

SP10
  • N° du produit (Fournisseur)

    200-301-e34

    Fournisseur

    Rockland

    Fonction

    Synaptobrevin (VAMP) Antibody

    Réactivité croisée (Details)

    Anti-Synaptobrevin (VAMP) Antibody is directed against human synaptobrevin.

    Purification

    Anti-Synaptobrevin was IgM purified by chromatography from cell culture supernatant.

    Immunogène

    Anti-Synaptobrevin (VAMP) Monoclonal Antibody was produced in mouse by repeated immunizations with synaptic immunoprecipitate (crude) from human brain.

    Isotype

    IgM
  • Indications d'application

    Immunohistochemistry_Dilution: 1:100

    Western_Blot_Dilution: 1:1000

    Commentaires

    Anti-Synaptobrevin antibody has been tested in Western Blotting and IHC. Expect a band of approximately 16 kDa in size corresponding to the VAMP proteins in Western blot of rat brain lysate. Anti-Synaptobrevin antibody has also been demonstrated to work in immunohistochemistry on formalin fixed, vibratome sections, but does not work on paraffin sections. Specific conditions for reactivity should be optimized by the end user. Researchers should determine optimal titers for applications that are not stated below.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

    Date de péremption

    12 months
  • Antigène

    VAMP 1,2

    Autre désignation

    VAMP1/2

    Sujet

    Synonyms: Vesicle-associated membrane protein 1

    Background: Synaptobrevin (also VAMP) is an integral membrane protein of synaptic vesicles that plays a major role in the formation of larger SNARE complexes, along with SNAP-25 and syntaxin. Synaptobrevin has been shown to be essential for two fast synapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter release and fast endocytosis that mediates rapid recycling of synaptic vesicles. Decreased levels of synaptobrevin in human hippocampus and cortex have been correlated with cognitive defects in Alzheimer's disease.

    Gene Name: VAMP1/2

    ID gène

    6843

    UniProt

    P23763
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